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In addition, widely studied experimental NRF2 inducers encompass natural and synthetic compounds such as sulforaphane (SFN) (Ma et al., 2023), bardoxolone methyl (CDDO-Me) (Abed et al., 2015), and curcumin (Patel et al., 2020)

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Numerous natural compounds, including polyphenols, alkaloids, and terpenoids, have shown promising results as potential LDH inhibitors for disease treatment